A fly for Sly
نویسندگان
چکیده
منابع مشابه
181-184 Sly
Volume 29, Number 4, July/August 1997 better index of acceptability than does the former, they are constrained by the bias of selecting only those women willing to try the device. Selectivity, small sample size and data collection restrictions in previous research have inhibited attempts to differentiate among women unwilling to try the device, those willing to do so and those using the female ...
متن کامل132-136 Sly
likely than nonusers to engage in risky sexual behavior and that they are less likely than nonusers to rely on condoms. In some studies, condom use has been treated as one component of a sexual-risk index, which is then related to substance use. In other research, condom use has been treated as a separate independent variable, which is then related to substance use directly. In this article, we...
متن کاملSly Disease: Mucopolysaccharidosis Type VII.
A 6 month-old infant presenting with severe mitral regurgitation was found to have hepatosplenomegaly, corneal clouding, and Alder-Reilly granules in the leucocytes. Extremely low levels of beta glucuronidase confirmed the diagnosis of Sly disease (Mucopolysaccharidosis VII). This is the first case of MPS VII reported from India.
متن کاملMissense models [Gustm(E536A)Sly, Gustm(E536Q)Sly, and Gustm(L175F)Sly] of murine mucopolysaccharidosis type VII produced by targeted mutagenesis.
Human mucopolysaccharidosis VII (MPS VII, Sly syndrome) results from a deficiency of beta-glucuronidase (GUS) and has been associated with a wide range in severity of clinical manifestations. To study missense mutant models of murine MPS VII with phenotypes of varying severity, we used targeted mutagenesis to produce E536A and E536Q, corresponding to active-site nucleophile replacements E540A a...
متن کاملSly Represses Gene Expression in Sex Chromosomes
The nuclei of eukaryotic cells can be thought of as a library containing the molecular ‘‘recipes,’’ or genes, for constructing the proteins and ribonucleic acid molecules used by a cell. Within the library, genes are grouped together into ‘‘books,’’ known as chromosomes, which consist of linear strands of DNA wrapped around specialized DNA-interacting proteins. Human body cells have 46 chromoso...
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ژورنال
عنوان ژورنال: Lab Animal
سال: 2019
ISSN: 0093-7355,1548-4475
DOI: 10.1038/s41684-018-0232-3